Trends in psychiatric hospitalization for alcohol and drugs in Castilla y León between 2005 and 2015. / Tendencias en la hospitalización psiquiátrica por alcohol y drogas en Castilla y León entre 2005 y 2015.

It has been estimated that alcohol, tobacco, and illicit drugs were responsible for more than 10 million deaths worldwide in 2016, and there are many opportunities for improvement. Regarding innovative data analysis, advances have been made in the extraction of information from administrative databases for analytics purposes. We studied trends in hospitalization rates for alcohol and drug abuse over eleven years with Joinpoint Trend Analysis software. This is a descriptive study of cross-associations in 3,758 hospital admissions of patients admitted with a main diagnosis of alcohol and drug abuse or dependence in psychiatry units of public health centres of Castilla y León (Spain) between 2005 and 2015. Hospitalization trends for alcohol and drug related conditions declined over the eleven-year period. Separately, there was a statistically significant decrease in alcohol and cocaine related conditions, but a strong upward trend in cannabis related conditions between 2013 and 2015. Alcohol was the main cause of admission to psychiatric units with a diagnosis of addiction. In the 11 years researched, there was a progressive and constant reduction in admissions for substance use except for cannabis. The innovative statistical methodology has already proven to be useful for identifying trends and changes in different pathologies over time.

A nivel mundial, se ha estimado que el alcohol, el tabaco y las drogas han sido responsables de más de 10 millones de muertes en 2016, y que existe mucho margen para reducir la mortalidad. Se han realizado avances en la extracción de información de bases de datos administrativas con el fin de analizar grandes volúmenes de datos sanitarios. Hemos estudiado las tendencias en las tasas de hospitalización con diagnóstico de adicción a alcohol y drogas durante once años con el software Joinpoint Trend Analysis. Se trata de un estudio descriptivo de asociación cruzada de 3.758 ingresos hospitalarios de pacientes con diagnóstico principal de abuso o dependencia de alcohol y drogas en unidades de Psiquiatría de centros públicos de Castilla y León entre 2005 y 2015. Las tendencias en la hospitalización por adicción al alcohol y/o drogas disminuyeron a lo largo de los once años. Además de una reducción estadísticamente significativa de los ingresos por alcohol y cocaína, se apreció una fuerte tendencia al alza en los ingresos por cannabis entre 2013 y 2015. El alcohol fue durante todo el periodo de estudio la principal causa de ingreso y el que más días de hospitalización ha generado. No obstante, en los 11 años se observó una reducción progresiva y constante en los ingresos por todas las sustancias a excepción del cannabis. La metodología utilizada ya ha demostrado ser muy útil para identificar cambios de tendencias en diferentes patologías.

Tendencias en la hospitalización psiquiátrica por alcoholy drogas en Castilla y León entre 2005 y 2015 / Trends in psychiatric hospitalization for alcohol and drugs in Castilla y León between 2005 and 2015

A nivel mundial, se ha estimado que el alcohol, el tabaco y las drogashan sido responsables de más de 10 millones de muertes en 2016, yque existe mucho margen para reducir la mortalidad. Se han realizadoavances en la extracción de información de bases de datos administrativas con el fin de analizar grandes volúmenes de datos sanitarios. Hemosestudiado las tendencias en las tasas de hospitalización con diagnóstico de adicción a alcohol y drogas durante once años con el softwareJoinpoint Trend Analysis. Se trata de un estudio descriptivo de asociación cruzada de 3.758 ingresos hospitalarios de pacientes con diagnóstico principal de abuso o dependencia de alcohol y drogas en unidadesde Psiquiatría de centros públicos de Castilla y León entre 2005 y 2015.Las tendencias en la hospitalización por adicción al alcohol y/o drogasdisminuyeron a lo largo de los once años. Además de una reducciónestadísticamente significativa de los ingresos por alcohol y cocaína, seapreció una fuerte tendencia al alza en los ingresos por cannabis entre2013 y 2015. El alcohol fue durante todo el periodo de estudio la principal causa de ingreso y el que más días de hospitalización ha generado.No obstante, en los 11 años se observó una reducción progresiva y constante en los ingresos por todas las sustancias a excepción del cannabis.La metodología utilizada ya ha demostrado ser muy útil para identificarcambios de tendencias en diferentes patologías. (AU)

It has been estimated that alcohol, tobacco, and illicit drugs were responsible for more than 10 million deaths worldwide in 2016, andthere are many opportunities for improvement. Regarding innovativedata analysis, advances have been made in the extraction of information from administrative databases for analytics purposes. We studiedtrends in hospitalization rates for alcohol and drug abuse over elevenyears with Joinpoint Trend Analysis software. This is a descriptive studyof cross-associations in 3,758 hospital admissions of patients admittedwith a main diagnosis of alcohol and drug abuse or dependence inpsychiatry units of public health centres of Castilla y León (Spain)between 2005 and 2015. Hospitalization trends for alcohol and drugrelated conditions declined over the eleven-year period. Separately,there was a statistically significant decrease in alcohol and cocainerelated conditions, but a strong upward trend in cannabis relatedconditions between 2013 and 2015. Alcohol was the main cause ofadmission to psychiatric units with a diagnosis of addiction. In the11 years researched, there was a progressive and constant reductionin admissions for substance use except for cannabis. The innovativestatistical methodology has already proven to be useful for identifyingtrends and changes in different pathologies over time. (AU)

Hospitalization trends and chronobiology for mental disorders in Spain from 2005 to 2015.

Rhythm research has had a long tradition in psychiatry, especially in affective disorders. The study of trends in incidence plays a central role in epidemiology and public health. The aims of this research were to describe the socio-demographic and clinical characteristics of persons admitted for psychiatric hospitalization and their trends and periodicity in cases (global and by groups) in Spain over the 11 year study span. We conducted a cross-sectional study of the hospital discharge database of Castilla y León from 2005 to 2015, selecting hospitalizations for psychiatric reasons. Trends in the rates of hospitalization were studied by joinpoint regression analysis. Time series analysis for periodicities was done by spectral analysis, fast Fourier transform, and cosinor analysis. Some 49501 hospitalizations due to psychiatric disorders, out of 2717192 hospital admissions, took place during the study span. Hospitalizations for psychosis were frequent (15949, 32.2%), while such for eating disorders were infrequent, but showed the highest average stay (28 days) and DRG relative weight (2.41). The general trend was a statistically significant 2% annual increase in psychiatric hospitalizations over the 11 year span; substance abuse was the only exception to this trend. The whole population and the subgroups of psychosis and bipolar disorders showed significant circannual (one-year) variation in admissions. The rhythm percentage of the global group was 11.4%, while the rhythm percentages of the psychosis, bipolar, and eating disorders were 17.1%, 17.5%, and 9.6%, respectively (p < .05).

The Impact of COVID-19 Pandemic on the Castile and Leon Addiction Treatment Network: A Real-Word Experience.

Background: Patients suffering from addiction are a vulnerable group in the midst of COVID-19, so their healthcare is considered essential. In this paper, the measures and responses of the Drug Addiction Assistance Network of Castile and Leon (DAACYL) in Spain during the first 6 weeks of the COVID-19 pandemic are explained. The aim is that this experience could be useful in places where this problem will continue and could help future interventions. Methods: A telephone survey was carried out as the main methodology, to collect information for the subsequent organization and repercussion on professionals and patients. This was carried out by the heads of the 18 DAACYL units. Among the interventions applied, the following stand out: implantation of telemedicine techniques, restriction of daily methadone dispensing, suspension of urine controls and initiation of care programs for the homeless. Results: As a result of these interventions, the professionals observed that patients are less demanding and mostly stable, with a low percentage of relapses. An increase in the consumption of alcohol and benzodiazepines have been reported as more common among people who relapse. Furthermore, the prevalence of COVID-19 infection in the sample is minimal; therefore, different hypotheses should be considered as an explanation (infra-diagnosis, immune system used to aggression, possible anti-inflammatory effect of some psychotropic drugs and a greater perception of danger against infection than the general population). Conclusions: The rapid adaptation and successful implementation of DAACYL have had satisfactory results. On the other hand, the prevention of the possible increase in the development of behavioral addictions and the use of homemade drugs should be considered.

Hospitalization and Socio-Health Care for Dementia in Spain.

Dementias are brain diseases that affect long-term cognitive and behavioral functions and cause a decrease in the ability to think and remember that is severe enough to disturb daily functioning. In Spain, the number of people suffering from dementia is rising due to population ageing. Reducing admissions, many of them avoidable, would be advantageous for patients and care-providers. Understanding the correlation of admission of people with dementia and its trends in hospitalization would help us to understand the factors leading to admission. We conducted a cross-sectional study of the hospital discharge database of Castilla y León from 2005 to 2015, selecting hospitalizations for dementia. Trends in hospitalizations by year and age quartiles were studied by joinpoint regression analysis. 2807 out of 2,717,192 total hospitalizations (0.10%) were due to dementias; the main groups were degenerative dementia (1907) followed by vascular dementia (607). Dementias are not a major cause of hospitalization, but the average stay and cost are high, and many of them seem avoidable. Decreasing trends were detected in hospitalization rates for all dementias except for the group of mild cognitive impairment, which grew. An increasing-decreasing joinpoint detected in 2007 for vascular dementia and the general downward hospitalization trends for most dementias suggest that socio-health measures established since 2007 in Spain might play a key role in reducing hospitalizations.

Trends in Psychiatric Hospitalization of Children and Adolescents in Spain between 2005 and 2015.

Eating disorders are on top of chronic conditions in children and adolescents, and the most severe cases may require hospitalization. Inpatient psychiatric treatment is one of the most expensive ones and therefore the efforts when treating eating disorders should focus on avoiding and shortening admissions, as well as preventing readmissions. Advances in of eating disorders treatment lie in an accurate knowledge of those patients requiring admission. This study examined the Conjunto Mínimo Básico de Datos-the largest public hospitalization database in Spain-to estimate the prevalence of eating and other psychiatric disorders during childhood and adolescence. It is a cross-sectional study of the hospital discharges in Castilla y León (Spain) from 2005 to 2015, in which patients under 18 years old with a psychiatric diagnosis at discharge were selected. Trends in the rates of hospitalization/1000 hospitalizations per year were studied by joinpoint regression analysis. Conclusions: eating disorders were the only group that presented an upward and continuous trend throughout the study period. This statistically significant increase showed an annual change of 7.8%.

Acoso escolar / Bullying

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Usefulness of Pharmacogenetic Analysis in Psychiatric Clinical Practice: A Case Report.

There are many factors involved in the effectiveness and efficiency of psychiatric drug treatment. One of them is psychotropic drug metabolism, which takes place mostly in the liver through the P450 enzyme system. However, there are genotypic variants of this system's enzymes that can directly affect both the efficacy and the onset of side effects of a given therapeutic regimen. These genotypic changes could partly explain the lack of efficacy of treatment in certain patients. We report the case of a patient diagnosed with bipolar type I disorder that presented multiple and frequent manic episodes in which the efficacy and tolerability of several pharmacological regimens with mood stabilizers and antipsychotics was scarce. The choice of medical treatment should be based on its efficacy and side effect profile. This decision can be made more accurately using the information provided by pharmacogenetic analysis. This case illustrates the importance of pharmacogenetic studies in clinical practice. The results of pharmacogenetic analysis helped to decide on a better treatment plan to achieve clinical improvement and reduce drug-induced adverse effects.

Software educativo para la enseñanza de la Propedéutica Clínica y Semiología Médica en idioma inglés / Training software for the teaching of the Clinical Propedeutics and medical Semiology in the English language

Fundamento: la enseñanza del idioma inglés constituye una estrategia curricular de esencial significación para el desarrollo integral del estudiante de Medicina. Objetivo: diseñar un software educativo que integre los tópicos de la asignatura Propedéutica Clínica y Semiología Médica en idioma inglés. Métodos: se desarrolló una investigación de desarrollo en la Facultad de Medicina de la Universidad de Ciencias Médicas de Villa Clara en el curso 2012-2013. Se utilizaron métodos teóricos para la interpretación y procesamiento de la información y los referentes teóricos del tema; empíricos: análisis documental de los programas y orientaciones metodológicas, y la encuesta en su modalidad de cuestionario a estudiantes de habla inglesa del área clínica de la carrera de Medicina para comprobar la efectividad del producto en su puesta en práctica. Resultados: fue diseñado un producto informático fundamentado en el programa docente de la asignatura y la estrategia curricular de idioma inglés, durante la comprobación de la efectividad del producto por su puesta en práctica se manifestó una variación significativa del nivel del conocimiento de los estudiantes, luego del uso del software. Conclusiones: el producto fue valorado satisfactoriamente según el criterio de especialistas como pertinente, necesario y útil para la asignatura, de gran aplicabilidad, y profundidad en los contenidos tratados, con agradable interfaz de usuario; la multimedia fue efectiva durante su puesta en práctica. Constituye una adecuada herramienta para elevar el nivel de conocimientos de la asignatura.

Background: the teaching of the English language constitutes a meaningful curricular strategy for the comprehensive development of the Medicine student. Objective: to design a training software that integrates the topics of the Clinical Propedeutics and medical Semiology subject in the English language. Methods: a research and development investigation was carried out in the Medicine Faculty of Villa Clara University of Medical Sciences in the academic year 2012-2013. Theoretical methods were used for the interpretation and processing of information and the theoretical groundwork on the topic; empiric ones: documental analysis of the programs and methodological orientations, and the survey in the questionnaire modality was applied to English-speaking students of the clinical area of the Medicine career to check the effectiveness of the product in its implementation. Results: a computing product based on the teaching program of the subject and the curricular strategy of the English language was designed, the testing of the effectiveness of the product during its implementation showed a significant variation of the level of the student´s knowledge, after the training with the software. Conclusions: the product was satisfactorily valued according to the specialist´s criteria as pertinent, necessary and useful for the subject, with great applicability, and depth in the treated contents, with pleasant user interface; the multimedia was effective during its implementation. It constitutes an appropriate tool to elevate the knowledge level on the subject.

Software educativo para la enseñanza de la Propedéutica Clínica y Semiología Médica en idioma inglés / Training software for the teaching of the Clinical Propedeutics and medical Semiology in the English language

Fundamento: la enseñanza del idioma inglés constituye una estrategia curricular de esencial significación para el desarrollo integral del estudiante de Medicina. Objetivo: diseñar un software educativo que integre los tópicos de la asignatura inglés. Fundamento: la enseñanza del idioma inglés constituye una estrategia curricular de esencial significación para el desarrollo integral del estudiante de Medicina. Objetivo: diseñar un software educativo que integre los tópicos de la asignatura Propedéutica Clínica y Semiología Médica en idioma inglés(AU)